I agree with ionFish that it's a good idea to use these new technologies, but you should keep your users on your mind all time when you're writing the codes.
Like many other users here, I have most recent versions of different web browsers too, but I mainly use Firefox, sometimes Chrome, and rarely the IE. When I started making my first website, I used some super cool and super easy codes to build a lightweight and yet beautiful website. I assumed everyone should have a modern browser nowadays, I was wrong! with a look at my visitors stats I noticed I have many visitors with very old browsers, and needless to say, none of them could see my cool CSS and HTML5 designs...
IMO, you should first focus on making your content available to everyone, don't forget there are many users who never install any third-party browser and sometimes they even forget to update the browser that came with their OS.