First, it should be noted that any difference between the configurations you mention is relatively minor.
They are all SE friendly in their own ways but in general:
- Keywords in the top level domain (e.g. www.KeywordExample.com) are given a little more weight.
- Subdomains (e.g. keyword.example.com) and directories (e.g. example.com/keyword) are pretty much the same.
- Subdomains are treated as separate, but usually related, sites.
In short, don't worry about it. Just create your site on a suitable domain with unique, relevant content. And remember that the biggest ranking factor in Google is still links. Any advantage from one URL configuration over another is insignificant once you have a handful of links pointing to your site.