Yes and often you need to do this to activate widgets. Schema.org has shoddy support for things like review-aggregate and doesnt support breadcrumbs (weird eh?). Reviews especially, it fails validators until you use a mix of Schema and Data-Vocabulary. Here are some random examples:
This Schema does not work for Product review summary:
<div itemscope itemprop="aggregateRating" itemtype="http://schema.org/AggregateRating">
<meta itemprop="ratingValue" content="<?php echo $rating; ?>" />
<meta itemprop="ratingCount" content="<?php echo $total_reviews; ?>" />
</div>
But this Data-Vocab does work for Product review summary:
<div itemscope itemprop="rating" itemtype="http://data-vocabulary.org/Rating">
<meta itemprop="average" content="<?php echo $rating; ?>" />
<meta itemprop="best" content="5" />
</div>
<meta itemprop="count" content="<?php echo $total_reviews; ?>" />
And for the actual review looping, Schema does work, but Data-Vocab is "depreciated":
<div itemscope itemprop="reviewRating" itemtype="http://schema.org/Rating">
<meta itemprop="worstRating" content="1" />
<meta itemprop="ratingValue" content="<?php echo $review['rating']; ?>" />
<meta itemprop="bestRating" content="5" />
</div>
Then in Breadcrumbs, Schema does not work, only Data-Vocab seems to fire snippets:
<span itemscope itemtype="http://data-vocabulary.org/Breadcrumb">
<?php echo $breadcrumb['separator']; ?><a href="<?php echo $breadcrumb['href']; ?>" itemprop="url"><span itemprop="title"><?php echo $breadcrumb['text']; ?></span></a>
</span>
I don't understand why they have not made Schema encompass all of the methodology of Data-Vocab...its strange to have to use the older methods to activate "new" Google widgets. Maybe im just crazy but thats how it seems to roll.