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Can we develop webpages that will work on both tablet, say Android, and Desktops/PCs (here I'm looking at non flash based web pages). Since I was looking at Sencha, do we need to use both Sencha Architect and Sencha Touch for the above development requirement?
Any other better alternatives?
The answer is yes, you can. Assuming you're building the website from scratch rather than using a content management system then basing your site around something like the Twitter Bootstrap framework http://twitter.github.com/bootstrap/ will likely give you the flexibility you're looking for.
If you want the website to feel exactly like a mobile app on a mobile device then generally you either need two versions of your site or a system which utilizes mobile or desktop templates depending on the requesting browser (all web scripting languages can be used to do this but it's extract design work).
You can build a 'mobile first' design using something like Sencha Touch (webkit browsers only) or the more cross platform jQuery Mobile framework: http://jquerymobile.com/
It depends on what you want: You could create a website that works well for many clients e.g. by applying the concept of Responsive Design. For the fun of it, got to the site of Sylvester Stallone and resize your browser window to see how the page adapts.
Or you create a website with a strong focus on the mobile (or tablet) device that looks like a native app - then use frameworks like that from Sencha or JQuery Mobile. In this case you go the route of creating something like a Web Application but not a website for the average visitor. For Sencha: You don't need Architect but it will help you speed up the interface part.
Another way would be a combination, let's say you have Wordpress, choose a Theme that uses responsive layout and install a plugin that delivers another themed variant of the page just for mobile devices.
